First of all the hypothesis behind antidepressants and atypical antipsychotics is backwards. Serotonin is not low in depression, anxiety, etc. What is low in those conditions is the ability to break down or metabolize serotonin with the end result being elevated serotonin levels. What “Selective Serotonin Reuptake Inhibitors” means is that these drugs inhibit the reuptake or metabolism of serotonin thus causing the serotonin to rise even higher compounding the initial problem. Then when serotonin levels become too high the end result is Serotonin Syndrome – a condition which can cause death by multiple organ failure. This was the cause of the death of Anna Nicole Smith’s 20 year old son, Daniel.